Schwannoma with bone differentiation in a dog

Abstract

A schwannoma with bone differentiation was diagnosed in a seven-year-old German Shepherd female dog. Clinical signs were those of limping and proprioceptive and neurological deficits. Superficial and deep sensitivity were lower and muscle atrophy of the left forelimb was marked. Two subscapular masses were detected at examination. Microscopic analysis of the masses disclosed a pronounced proliferation of either palisading or loosely arranged within a myxoid tissue spindle neoplastic cells intermingled with bone tissue islands. The neoplasm was positive for vimentin, S100 protein and GFAP.