Immunophenotyping of Thymic Lymphoma in a Nelore Cow

Authors

  • Paulo H. Sampaio Graduate student of FCAV – Unesp/Jaboticabal - Programa de Medicina Veterinária Author
  • Otávio L. Fidelis Junior Graduate student of FCAV – Unesp/Jaboticabal - Programa de Medicina Veterinária Author
  • Daniela J. de Queiroz Graduate student of FCAV – Unesp/Jaboticabal - Programa de Medicina Veterinária Author
  • Luciana M. C. Soares Graduate student of FCAV – Unesp/Jaboticabal - Programa de Medicina Veterinária Author
  • Pamela R. R. Moreira Graduate student of FCAV – Unesp/Jaboticabal - Programa de Medicina Veterinária Author
  • Rosemeri O. Vasconcelos Professor of FCAV – Unesp/Jaboticabal Author
  • Luiz C. Marques Professor of FCAV – Unesp/Jaboticabal Author
  • Antonio C. Alessi Professor of FCAV – Unesp/Jaboticabal Author

Keywords:

Immunohistochemistry, thymic lymphoma, CD8 T cell, Nelore breed

Abstract

Thymic lymphoma is a malignant lymphoid neoplasm that affects several species, including cattle. This type of neoplasia can lead to death due to malignant cell infiltration in different organs. The classification of this neoplasm may predict prognosis and response to treatment. Immunophenotyping is one of the ways to perform this classification. There are reports about the performance of immunohistochemistry (IHC) to classify thymic lymphoma only in taurine cattle, therefore the aim of this report is to describe the immunophenotype of a thymic lymphoma in a Nelore cow. Immunostaining was performed with monoclonal antibodies (CD79, CD4 and CD8). The tumor cells showed positive staining only for CD8 T lymphocytes, coinciding with the disease progression, since the T lymphoma type is more aggressive.

Author Biographies

  • Paulo H. Sampaio, Graduate student of FCAV – Unesp/Jaboticabal - Programa de Medicina Veterinária

    Graduate student of FCAV – Unesp/Jaboticabal - Programa de Medicina Veterinária

  • Otávio L. Fidelis Junior , Graduate student of FCAV – Unesp/Jaboticabal - Programa de Medicina Veterinária

    Graduate student of FCAV – Unesp/Jaboticabal - Programa de Medicina Veterinária

  • Daniela J. de Queiroz, Graduate student of FCAV – Unesp/Jaboticabal - Programa de Medicina Veterinária

    Graduate student of FCAV – Unesp/Jaboticabal - Programa de Medicina Veterinária

  • Luciana M. C. Soares, Graduate student of FCAV – Unesp/Jaboticabal - Programa de Medicina Veterinária

    Graduate student of FCAV – Unesp/Jaboticabal - Programa de Medicina Veterinária

  • Pamela R. R. Moreira, Graduate student of FCAV – Unesp/Jaboticabal - Programa de Medicina Veterinária

    Graduate student of FCAV – Unesp/Jaboticabal - Programa de Medicina Veterinária

  • Rosemeri O. Vasconcelos, Professor of FCAV – Unesp/Jaboticabal

    Professor of FCAV – Unesp/Jaboticabal

  • Luiz C. Marques, Professor of FCAV – Unesp/Jaboticabal

    Professor of FCAV – Unesp/Jaboticabal

  • Antonio C. Alessi, Professor of FCAV – Unesp/Jaboticabal

    Professor of FCAV – Unesp/Jaboticabal

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Published

2012-07-30

Issue

Vol. 5 No. 2 (2012): BJVP

Section

Artigos

How to Cite

Sampaio, P. H., Fidelis Junior , O. L., Queiroz, D. J. de, Soares, L. M. C., Moreira, P. R. R., Vasconcelos, R. O., Marques, L. C., & Alessi, A. C. (2012). Immunophenotyping of Thymic Lymphoma in a Nelore Cow. Brazilian Journal of Veterinary Pathology, 5(2), 94-98. https://bjvp.org.br/bjvp/article/view/128