Mixed thymoma in a German Shepherd dog

Case report

Authors

  • Enrique G. Dengues Departament of Veterinary Pathology, National University of Asunción (FCV-UNA), Paraguay. Author
  • Shyrley P. Amarilla Departament of Veterinary Pathology, National University of Asunción (FCV-UNA), Paraguay. Author
  • Isabel Grau Departament of Veterinary Pathology, National University of Asunción (FCV-UNA), Paraguay Author
  • Alvaro S. Werhle Departament of Veterinary Pathology, National University of Asunción (FCV-UNA), Paraguay Author
  • Kristel Kegler Graduate student. National University of Asunción (FCV-UNA), Paraguay Author
  • Ada G. Cino Graduate student. National University of Asunción (FCV-UNA), Paraguay Author
  • Andres A. R. Diaz Department of Veterinary Pathology, Facultad de Ciencias Veterinarias, Universidad Nacional de Asunción Author

Keywords:

Canine, thoracic neoplasia, thymoma, lymphocytes T, immunohistochemistry

Abstract

A thoracic neoplastic mass in a 6 years-old German Shepherd dog was examined. The dog had apathy, regurgitation, and ascites. A large mass occupying the cranioventral, medial and caudal mediastinum was found by X ray and ultrasonography. Grossly, a 27 x 23 x 12 cm encapsulated, multilobulated, and cystic mass was found. Firms adhesions were present between the neoplasm and the right and left cranial lung lobes. Histopathologically, the neoplastic cell population consisted of solids sheets of epithelial cells and aggregates or individual lymphocytes. By immunohistochemistry, proliferating epithelial cells were positive for keratin and lymphocytes were intensely positive for CD3, identifying them as T cells. Based on gross, histologic, and immunohistochemical findings, the neoplasm was diagnosed as a mixed thymoma.

Author Biographies

  • Enrique G. Dengues, Departament of Veterinary Pathology, National University of Asunción (FCV-UNA), Paraguay.

    Departament of Veterinary Pathology, National University of Asunción (FCV-UNA), Paraguay.

  • Shyrley P. Amarilla, Departament of Veterinary Pathology, National University of Asunción (FCV-UNA), Paraguay.

    Departament of Veterinary Pathology, National University of Asunción (FCV-UNA), Paraguay.

  • Isabel Grau, Departament of Veterinary Pathology, National University of Asunción (FCV-UNA), Paraguay

    Departament of Veterinary Pathology, National University of Asunción (FCV-UNA), Paraguay

  • Alvaro S. Werhle, Departament of Veterinary Pathology, National University of Asunción (FCV-UNA), Paraguay

    Departament of Veterinary Pathology, National University of Asunción (FCV-UNA), Paraguay

  • Kristel Kegler, Graduate student. National University of Asunción (FCV-UNA), Paraguay

    Graduate student. National University of Asunción (FCV-UNA), Paraguay

  • Ada G. Cino, Graduate student. National University of Asunción (FCV-UNA), Paraguay

    Graduate student. National University of Asunción (FCV-UNA), Paraguay

  • Andres A. R. Diaz, Department of Veterinary Pathology, Facultad de Ciencias Veterinarias, Universidad Nacional de Asunción

    Department of Veterinary Pathology, Facultad de Ciencias Veterinarias, Universidad Nacional de Asunción

Downloads

Published

2008-11-30

Issue

Vol. 1 No. 2 (2008): BJVP

Section

Artigos

How to Cite

Dengues, E. G., Amarilla, S. P., Grau, I., Werhle, A. S., Kegler, K., Cino, A. G., & Diaz, A. A. R. (2008). Mixed thymoma in a German Shepherd dog: Case report. Brazilian Journal of Veterinary Pathology, 1(2), 73-76. https://bjvp.org.br/bjvp/article/view/15