Acute and subclinical Ehrlichia canis infection and cortisol response to ACTH stimulation test

Authors

  • Mariana Cristina H. Rondelli Department of Veterinary Clinic and Surgery, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (Unesp), Jaboticabal-SP. Author
  • Thiago D. Munhoz Centro Universitário Barão de Mauá, Ribeirão Preto-SP. Author
  • Pâmela B. Catandi Autonomous veterinarian Author
  • Carla R. Freschi Department of Veterinary Pathology, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (Unesp), Jaboticabal-SP. Author
  • Reinaldo J. G. Palacios Junior Autonomous veterinarian Author
  • Rosângela Z. Machado Department of Veterinary Pathology, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (Unesp), Jaboticabal-SP. Author
  • Mirela Tinucci-Costa Department of Veterinary Clinic and Surgery, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (Unesp), Jaboticabal-SP Author

Keywords:

adrenal, dogs, canine ehrlichiosis, hormones

Abstract

Adrenocortical disturbances are associated with canine ehrlichiosis due to the immunological changes caused by infection and consequent inflammation. Thus, this study aimed to evaluate the occurrence of adrenocortical hormonal changes in dogs naturally infected with Ehrlichia canis (n=21) as confirmed by the presence of anti-E. canis antibodies (Dot-ELISA) and nested PCR (nPCR). Serum cortisol concentrations were assessed by radioimmunoassay before and one hour after ACTH stimulation. Ten healthy dogs were subjected to the same stimulation protocol and used as controls. The results revealed that the dogs with naturally acquired acute and subclinical ehrlichiosis secreted cortisol following ACTH stimulation in similar concentrations to those of healthy dogs.

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Published

2015-07-30

Issue

Vol. 8 No. 2 (2015): BJVP

Section

Artigos

How to Cite

Rondelli, M. C. H., Munhoz, T. D., Catandi, P. B., Freschi, C. R., Palacios Junior, R. J. G., Machado, R. Z., & Tinucci-Costa, M. (2015). Acute and subclinical Ehrlichia canis infection and cortisol response to ACTH stimulation test. Brazilian Journal of Veterinary Pathology, 8(2), 46-50. https://bjvp.org.br/bjvp/article/view/194