Chronic eosinophilic leukemia in an African hedgehog (Atelerix albiventris)

Authors

  • Daniela K. Escobar-Alarcón Departamento de Patología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Avenida Universidad 3000, Ciudad Universitaria, Delegación Coyoacán, D.F., 04510, México. Author
  • Alonso Reyes-Matute Departamento de Patología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Avenida Universidad 3000, Ciudad Universitaria, Delegación Coyoacán, D.F., 04510, México. Author
  • Adriana Méndez-Bernal Departamento de Patología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Avenida Universidad 3000, Ciudad Universitaria, Delegación Coyoacán, D.F., 04510, México. Author
  • Karina Flores-Pineda Departamento de Etología, Fauna silvestre y Animales de Laboratorio. Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Avenida Universidad 3000, Ciudad Universitaria, Delegación Coyoacán, D.F., 04510, México. Author
  • Alfonso López-Mayagoitia Departament of Pathology and Microbiology, Atlantic Veterinary College. University of Prince Edward Island, Charlottetown, PEI, Canada C1A 4P3. Author

Keywords:

wildlife diseases, neoplasia, eosinophilic leukemia, African hedgehog, Atelerix albiventris

Abstract

A 5-year-old African hedgehog (Atelerix albiventris) was presented to the veterinarian with history of anorexia and progressive weight loss. On clinical examination the mucous membranes were pale, and the skin exhibited extensive alopecia with crusting in all four limbs and tail. A large subcutaneous mass was palpated on the left lateral femur which subsequently was diagnosed histopathologically as a squamous cells carcinoma. The owner declined further tests and the patient returned home where it continued to deteriorate and finally died 90 days after initial presentation. The carcass was submitted for postmortem examination. Necropsy finding included an enlarged spleen with rounded borders and meaty pulp, hyperplastic bone marrow and multiple white foci in both kidneys. Tissues were submitted for cytology, histopathology and electron microscopy. Splenic cytology revealed a monomorphic population of granulocytes with cellular atypia which were most consistent with neoplastic eosinophils. Similar myeloid cells were also seen histologically in kidneys, liver, intestine, heart, skin and brain. The bone marrow was completely effaced with similar cellular infiltrates. Luna stain for eosinophils was positive in all tissues. Electron microscopy showed that neoplastic cells had granules and electron-lucent crystalloid characteristic of eosinophils. Based on these finding chronic eosinophilic leukemia was diagnosed, and to our knowledge, eosinophilic leukemia in hedgehogs is rarely reported in the literature.

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Published

2016-03-30

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Artigos

How to Cite

Escobar-Alarcón, D. K., Reyes-Matute, A., Méndez-Bernal, A., Flores-Pineda, K., & López-Mayagoitia, A. (2016). Chronic eosinophilic leukemia in an African hedgehog (Atelerix albiventris). Brazilian Journal of Veterinary Pathology, 9(1), 34-38. https://bjvp.org.br/bjvp/article/view/212