Multiple congenital encephalic malformations in a calf

Authors

  • Lorena F. Silva Universidade de Brasília (UnB), Hospital Veterinário de Grandes Animais, Laboratório de Diagnóstico Patológico Veterinário, Brasília, DF, Brazil. Author
  • Rogério E. Rabelo Universidade Federal de Goiás (UFG), Regional Jataí, Setor de Cirurgia de Grandes Animais, Jataí, GO, Brazil. Author
  • Guilherme P. Santos Universidade Federal de Goiás (UFG), Regional Jataí, Setor de Cirurgia de Grandes Animais, Jataí, GO, Brazil. Author
  • Oton L. R. Aguiar Universidade Federal de Goiás (UFG), Regional Jataí, Setor de Cirurgia de Grandes Animais, Jataí, GO, Brazil. Author
  • Luciana Sonne Universidade Federal do Rio Grande do Sul (UFRGS), Departamento de Patologia Clínica Veterinária, Porto Alegre, RS, Brazil. Author
  • Claudio S. L. Barros Universidade Federal de Mato Grosso do Sul (UFMS), Faculdade de Medicina Veterinária e Zootecnia, Campo Grande, MS, Brazil. Author
  • Fabiano J. F. de Sant’Ana Universidade de Brasília (UnB), Hospital Veterinário de Grandes Animais, Laboratório de Diagnóstico Patológico Veterinário, Brasília, DF, Brazil. Author

Keywords:

diseases of calves, neuropathology, central nervous system, cerebellar hypoplasia

Abstract

Multiple congenital malformations of the central nervous system are uncommonly described in domestic animals. A 7-days-old, female, Holstein calf was submitted for necropsy with a history of opisthotonus and permanent lateral recumbence. Clinical signs included apathy, abdominal breathing, occasional flexion of the forelimbs, and decreasing of the superficial and deep sensibility in all limbs. Necropsy and histopathology revealed cerebellar hypoplasia, stenosis of the mesencephalic aqueduct, fusion of the rostral and caudal colliculi, secondary hydrocephaly, villous hypertrophy of the choroid plexus and heterotopy of cerebellar cellular components. Immunohistochemical labeling for the antibody anti-BVDV in fragments of brain resulted negative, suggesting that this virus did not participate in the pathogenesis of these malformations.

Downloads

Published

2016-11-30

Issue

Section

Artigos

How to Cite

Silva, L. F., Rabelo, R. E., Santos, G. P., Aguiar, O. L. R., Sonne, L., Barros, C. S. L., & Sant’Ana, F. J. F. de. (2016). Multiple congenital encephalic malformations in a calf. Brazilian Journal of Veterinary Pathology, 9(3), 103-107. https://bjvp.org.br/bjvp/article/view/223