Metronomic chemotherapy for advanced diffuse hepatocellular carcinoma in a dog

Authors

  • Paloma Helena Sanches da Silva Department of Veterinary Clinic and Surgery, Federal University of Minas Gerais. Belo Horizonte – Minas Gerais Author
  • Mayara Coutinho Carlos de Souza University Vila Velha (UVV), Vila Velha, Espiríto Santo, Brazil Author
  • Ellen Bethânia de Oliveira Cavalcanti University Vila Velha (UVV), Vila Velha, Espiríto Santo Author
  • Victoria Bringhenti Fonseca Qualittas College. Pará-Belém, Brazil Author
  • Tatiany Luiza Silveira Department of General Pathology, Institute of Biological Sciences, Federal University of Minas Gerais. Belo Horizonte – Minas Gerais Author
  • Mayra Cunha Flecher University Vila Velha (UVV), Vila Velha, Espiríto Santo, Brazil Author
  • Geovanni Dantas Cassali Department of General Pathology, Institute of Biological Sciences, Federal University of Minas Gerais. Belo Horizonte – Minas Gerais Author
  • Rodrigo dos Santos Horta Department of Veterinary Clinic and Surgery, Federal University of Minas Gerais. Belo Horizonte – Minas Gerais Author

DOI:

https://doi.org/10.24070/bjvp.1983-0246.v14i3p199-205

Keywords:

Dog, Liver, Neoplasm, Metronomic Chemotherapy, Chlorambucil;, Low-dose naltrexone

Abstract

Primary liver tumors represent 0.6% to 1.3% of neoplasms in dogs. Hepatocellular carcinoma (HCC) is the most common liver tumor. It is divided into three morphological groups: massive, nodular and diffuse. The presumptive diagnosis is made through imaging tests, such as ultrasound, although confirmation is made by histopathology. Surgery remains the treatment of choice for massive tumors, but there is no standard treatment for nodular and diffuse forms. This study aimed to report a case of prolonged survival in a dog with diffuse HCC, treated with metronomic chemotherapy and palliative care including non-steroidal anti-inflammatory and low-dose naltrexone.

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Published

2021-11-30

Issue

Vol. 14 No. 3 (2021): BJVP

Section

Artigos

How to Cite

Silva, P. H. S. da, Souza, M. C. C. de, Cavalcanti, E. B. de O., Fonseca, V. B., Silveira, T. L., Flecher, M. C., Cassali, G. D., & Horta, R. dos S. (2021). Metronomic chemotherapy for advanced diffuse hepatocellular carcinoma in a dog. Brazilian Journal of Veterinary Pathology, 14(3), 199-205. https://doi.org/10.24070/bjvp.1983-0246.v14i3p199-205