True hermaphroditism in a wistar rat

Authors

  • R. Madheswaran Senior Research Scientist, Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Udyog Vihar, Gurgaon 122 015, Haryana Author
  • V. V. Pande Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India Author
  • P. Kalaiselvan Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India Author
  • K. Y. Mathur Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India Author
  • P. D. Shelar Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India Author
  • J. J. Bhelonde Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India Author
  • Venkatesha Udupa Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India Author
  • V. M. Shingatgeri Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India Author

Keywords:

Wistar rat, hermaphrodite, ovotestis, follicles, seminiferous tubules

Abstract

A rare case of true hermaphroditism was observed in a 9-week-old presumed female Wistar rat. This rat did not reveal any untoward clinical signs, food consumption, body weight gain and changes in haemato-biochemical parameters. Grossly, rat showed reduced size of the left ovary and shortened uterine horn. Microscopically, ovotestis was observed in the left ovarian tissue. Ovary consisted of numerous developing follicles at different stages of development with absence of corpora lutea. Developing testis contained seminiferous tubules lined with sertoli cells and sparse spermatogonial population. Left oviduct resembling developing epididymis consisting of tubules embedded in proliferating fibrous connective tissue, lined with multilayered ciliated columnar epithelial cells. Most of them were empty but, few had eosinophilic secretion and some of them contained exfoliated germ cells. Left uterine horn showed increased stromal connective tissue without proliferation of endometrial glands. A histopathological examination of left ovarian tissue implies a case of true hermaphroditism.

Author Biographies

  • R. Madheswaran , Senior Research Scientist, Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Udyog Vihar, Gurgaon 122 015, Haryana

    Senior Research Scientist, Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Udyog Vihar, Gurgaon 122 015, Haryana

  • V. V. Pande , Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India

    Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India

  • P. Kalaiselvan, Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India

    Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India

  • K. Y. Mathur , Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India

    Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India

  • P. D. Shelar, Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India

    Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India

  • J. J. Bhelonde, Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India

    Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India

  • Venkatesha Udupa, Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India

    Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India

  • V. M. Shingatgeri, Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India

    Drug Safety Evaluation, Ranbaxy Research Laboratories, Plot No. 20, Sector 18, Industrial area, Udyog Vihar, Gurgaon 122 015, Haryana, India

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Published

2009-11-30

Issue

Vol. 2 No. 2 (2009): BJVP

Section

Artigos

How to Cite

Madheswaran , R., Pande , V. V., Kalaiselvan, P., Mathur , K. Y., Shelar, P. D., Bhelonde, J. J., Udupa, V., & Shingatgeri, V. M. (2009). True hermaphroditism in a wistar rat. Brazilian Journal of Veterinary Pathology, 2(2), 91-94. https://bjvp.org.br/bjvp/article/view/36