Histopathological and immunohistochemical characterization of a mixed tubule papillary thyroid carcinoma in a Nellore cow

Authors

  • Iolanda Simões Braga Department of Veterinary Clinic, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP) Author
  • Pedro Pol Ximenes Department of Veterinary Clinic, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP) Author
  • Fernando Carmona Dinau Department of Veterinary Clinic, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP) Author
  • Fernanda Barthelson Carvalho de Moura Department of Veterinary Clinic, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP) Author
  • Isabeli Joaquim Contel Department of Veterinary Clinic, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP) Author
  • Giovanna Gati de Souza Department of Veterinary Clinic, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP) Author
  • Isadora Fernanda Pelaquim Department of Veterinary Clinic, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Author
  • Noeme Sousa Rocha Department of Veterinary Clinic, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP) Author

DOI:

https://doi.org/10.24070/bjvp.1983-0246.v17i2p108-111

Keywords:

bovine, thyroid carcinoma, histopathology, immunohistochemistry

Abstract

Reports on thyroid carcinomas in bovines are scarce. An 18-year-old Nellore cow was referred to a veterinary hospital due to lateral recumbency lasting one day after falling on irregular terrain. The patient was clinically diagnosed with spinal cord injury. Necropsy and histopathology revealed a thyroid tubule papillary carcinoma. Immunohistochemical analysis revealed discrete positive cells for calcitonin, moderately positive cells for thyroid transcription factor 1 (TTF-1), and strongly positive cells for thyroglobulin in the thyroid gland. Thus, this report describes a case of a mixed tubule papillary carcinoma derived from both medullary and follicular cells in a Nellore cow.

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Published

2024-07-30

Issue

Vol. 17 No. 2 (2024): BJVP

Section

Articles

How to Cite

Braga, I. S., Ximenes, P. P., Dinau, F. C., Moura, F. B. C. de, Contel, I. J., Souza, G. G. de, Pelaquim, I. F., & Rocha, N. S. (2024). Histopathological and immunohistochemical characterization of a mixed tubule papillary thyroid carcinoma in a Nellore cow. Brazilian Journal of Veterinary Pathology, 17(2), 108-111. https://doi.org/10.24070/bjvp.1983-0246.v17i2p108-111