COX-2 and TGF- expression in proliferative disorders of canine prostate

Authors

  • Marcela M.P. Rodrigues Veterinary Pathology Service, UNESP, Botucatu, Brazil Author
  • Giovana W. Di Santis Faculdade de Medicina Veterinária, Universidade Estadual de Londrina, Londrina, Brazil Author
  • Veridiana M.B.D. de Moura Faculdade de Medicina Veterinária, Universidade Federal de Goiás, Brazil Author
  • Renée L. Amorim Veterinary Pathology Service, UNESP, Botucatu, Brazi Author

Keywords:

carcinoma prostate, COX-2, dog, preneoplastic lesions, TGF-

Abstract

COX-2 and TGF- expression was determined in order to correlate non-neoplastic lesions, preneoplastic lesions and carcinoma in the prostate of dogs. The results show that neoplastic and preneoplastic lesions express more COX-2 and TGF- when compared to carcinomas, which suggests these proteins may cooperate in the process of prostate tumorigenesis.

Author Biographies

  • Marcela M.P. Rodrigues, Veterinary Pathology Service, UNESP, Botucatu, Brazil

    Veterinary Pathology Service, UNESP, Botucatu, Brazil

  • Giovana W. Di Santis, Faculdade de Medicina Veterinária, Universidade Estadual de Londrina, Londrina, Brazil

    Faculdade de Medicina Veterinária, Universidade Estadual de Londrina, Londrina, Brazil

  • Veridiana M.B.D. de Moura, Faculdade de Medicina Veterinária, Universidade Federal de Goiás, Brazil

    Faculdade de Medicina Veterinária, Universidade Federal de Goiás, Brazil

  • Renée L. Amorim, Veterinary Pathology Service, UNESP, Botucatu, Brazi

    Veterinary Pathology Service, UNESP, Botucatu, Brazi

Downloads

Published

2010-05-30

Issue

Vol. 3 No. 1 (2010): BJVP

Section

Artigos

How to Cite

Rodrigues, M. M., Di Santis, G. W., Moura, V. M. de, & Amorim, R. L. (2010). COX-2 and TGF- expression in proliferative disorders of canine prostate. Brazilian Journal of Veterinary Pathology, 3(1), 31-36. https://bjvp.org.br/bjvp/article/view/46