Primary brain T-cell lymphoma in a cat

Authors

  • Fabiano J. F. de Sant’Ana Laboratory of Veterinary Pathology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil Author
  • Janildo L. Reis Junior Department of Pathology, College of Veterinary Medicine, The University of Georgia, Athens, GA, USA Author
  • Corrie C. Brown Department of Pathology, College of Veterinary Medicine, The University of Georgia, Athens, GA, USADepartment of Pathology, College of Veterinary Medicine, The University of Georgia, Athens, GA, USA Author
  • Ingeborg M. Langohr Diagnostic Center for Population and Animal Health, Michigan State University, Lansing, MI, USA Author
  • Claudio S. L. Barros Laboratory of Veterinary Pathology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil Author

Keywords:

cat diseases, T-cell lymphoma, CNS neoplasia, neuropathology

Abstract

A 10-year-old, female, mixed-breed cat was presented for necropsy with history of incoordination, circling and nystagmus or fixed gaze. Grossly, slight asymmetry was observed in the right telencephalic hemisphere, mainly in the pyriform lobe. Histologically, sheets of small round neoplastic cells were observed in the pons, midbrain, thalamus and in the subcortical white matter of the parietal, occipital and pyriform lobes. Neoplastic cells were strongly labeled with anti-CD3 antibody by means of immunohistochemistry. Anti-BLA36, CD79a and MAC387 failed to label the neoplastic cells. Based on the histopathological findings and on the immunohistochemical results, a diagnosis of primary brain T-cell lymphoma was made.

Author Biographies

  • Fabiano J. F. de Sant’Ana, Laboratory of Veterinary Pathology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil

    Laboratory of Veterinary Pathology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil

  • Janildo L. Reis Junior, Department of Pathology, College of Veterinary Medicine, The University of Georgia, Athens, GA, USA

    Department of Pathology, College of Veterinary Medicine, The University of Georgia, Athens, GA, USA

  • Corrie C. Brown, Department of Pathology, College of Veterinary Medicine, The University of Georgia, Athens, GA, USADepartment of Pathology, College of Veterinary Medicine, The University of Georgia, Athens, GA, USA

    Department of Pathology, College of Veterinary Medicine, The University of Georgia, Athens, GA, USA

  • Ingeborg M. Langohr, Diagnostic Center for Population and Animal Health, Michigan State University, Lansing, MI, USA

    Diagnostic Center for Population and Animal Health, Michigan State University, Lansing, MI, USA

  • Claudio S. L. Barros, Laboratory of Veterinary Pathology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil

    Laboratory of Veterinary Pathology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil

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Published

2010-05-30

Issue

Vol. 3 No. 1 (2010): BJVP

Section

Artigos

How to Cite

Sant’Ana, F. J. F. de, Reis Junior, J. L., Brown, C. C., Langohr, I. M., & Barros, C. S. L. (2010). Primary brain T-cell lymphoma in a cat. Brazilian Journal of Veterinary Pathology, 3(1), 56-59. https://bjvp.org.br/bjvp/article/view/51