Canine Transmissible Venereal Tumors

Aspects Related to Programmed Cell Death

Authors

  • Daniela Stockmann UNESP - University of São Paulo State, Faculdade de Medicina Veterinária, Laboratory of Virology Author
  • Heitor F. Ferrari UNESP - University of São Paulo State, Faculdade de Medicina Veterinária, Laboratory of Virology Author
  • Alexandre L. Andrade UNESP - University of São Paulo State, Faculdade de Medicina Veterinária, Laboratory of Virology Author
  • Rodrigo A. Lopes UNESP - University of São Paulo State, Faculdade de Medicina Veterinária, Laboratory of Virology Author
  • Tereza C. Cardoso UNESP - University of São Paulo State, Faculdade de Medicina Veterinária, Laboratory of Virology Author
  • Maria C. R. Luvizotto UNESP - Faculdade de Medicina Veterinária, Laboratory of Animal Pathology Author

Keywords:

CTVT, Sticker´s sarcoma, apoptosis, dog

Abstract

Canine transmissible venereal tumor (CTVT) is a neoplasm transmitted by the physical transfer of viable tumor cells by direct contact with injured skin and/or mucous tissue. These cells can transpose across histocompatibility barriers into unrelated hosts. This review focuses on the biology of apoptosis and the interaction of proteins involved in this process, as well as p53, p63 and the antiapoptotic protein Bcl-2. As such, this disease offer unique opportunity to study the biology of transplantable tumours and the interaction of proteins involved in apoptosis process and the prognosis of CTVT.

Author Biographies

  • Daniela Stockmann, UNESP - University of São Paulo State, Faculdade de Medicina Veterinária, Laboratory of Virology

    UNESP - University of São Paulo State, Faculdade de Medicina Veterinária, Laboratory of Virology

  • Heitor F. Ferrari, UNESP - University of São Paulo State, Faculdade de Medicina Veterinária, Laboratory of Virology

    UNESP - University of São Paulo State, Faculdade de Medicina Veterinária, Laboratory of Virology

  • Alexandre L. Andrade, UNESP - University of São Paulo State, Faculdade de Medicina Veterinária, Laboratory of Virology

    UNESP - University of São Paulo State, Faculdade de Medicina Veterinária, Laboratory of Virology

  • Rodrigo A. Lopes, UNESP - University of São Paulo State, Faculdade de Medicina Veterinária, Laboratory of Virology

    UNESP - University of São Paulo State, Faculdade de Medicina Veterinária, Laboratory of Virology

  • Tereza C. Cardoso, UNESP - University of São Paulo State, Faculdade de Medicina Veterinária, Laboratory of Virology

    UNESP - University of São Paulo State, Faculdade de Medicina Veterinária, Laboratory of Virology

  • Maria C. R. Luvizotto, UNESP - Faculdade de Medicina Veterinária, Laboratory of Animal Pathology

    UNESP - Faculdade de Medicina Veterinária, Laboratory of Animal Pathology

Downloads

Published

2011-03-30

Issue

Vol. 4 No. 1 (2011): BJVP

Section

Artigos

How to Cite

Stockmann, D., Ferrari, H. F., Andrade, A. L., Lopes, R. A., Cardoso, T. C., & Luvizotto, M. C. R. (2011). Canine Transmissible Venereal Tumors: Aspects Related to Programmed Cell Death. Brazilian Journal of Veterinary Pathology, 4(1), 67-75. https://bjvp.org.br/bjvp/article/view/81