v.13, n.3, 9
Case Report
Uterine leiomyosarcoma with secondary acute hemoabdomen in a goat
Daniel R. Rissi, Nicole M. Nemeth
Abstract
Neoplasms of the reproductive tract are uncommonly reported in goats. Here we describe a case of sudden death caused by acute hemoabdomen due to a ruptured uterine leiomyosarcoma in a 7-year-old female mixed breed goat. Gross changes included oral and ocular pallor, as well as 3 liters of blood and blood clots in the abdominal cavity. The uterine body wall was irregularly thickened and firm, and had a 2 cm in diameter, transmural perforation. The uterine lumen was filled with dark red to brown blood clots admixed with friable necrotic material. Histologically, a poorly-demarcated neoplasm expanded and effaced the uterine wall. The neoplasm consisted of densely packed bundles and streams of elongate neoplastic cells with moderate pleomorphism and abundant eosinophilic cytoplasm and elongate nuclei with coarsely stippled chromatin. The mitotic count was 4 per 2.37 mm2. Multiple areas of necrosis and clusters of lymphocytes and plasma cells were present throughout the neoplasm. Neoplastic cells exhibited diffuse immunolabeling for smooth muscle actin and patchy immunolabeling for desmin, consistent with a uterine leiomyosarcoma.
Key words: uterus, leiomyosarcoma, goat, reproductive pathology.
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