Vol. 6, n. 2 – July 2013

v6n2

v.6, n.2, 11

Editor’s Viewpoint
The Evolution of Diagnostic Pathology
Aline Rodrigues Hoffmann

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v.6, n.2, 12

Original Full Paper
Synergistic Pathological Effect of Mycoplasma gallisepticum with other Infectious Organisms in Layer Chickens
Soundarapandian Sivaseelan, Shanmugasamy Malmarugan, Perumal Balachandran, Gurusamipalayam Amirthalingam Balasubramaniam
Abstract

Synergistic pathological effect of Mycoplasma gallisepticum with other infectious organisms in layer chickens was evaluated in 70 commercial layer chicken farms. Newcastle disease virus and infectious bronchitis virus were confirmed by haemagglutination inhibition test (HI), and Escherichia coli, Pasteurella multocida, Haemophilus paragallinarum andOrnithobacterium rhinotracheale were confirmed by their growth characteristics on agar media and Gram’s staining. PCR technique was used for the confirmation of Mycoplasma gallisepticum. The mortality rates observed in the occurrence of individual diseases were synergistically increased when they combined with chronic respiratory disease (CRD), which was clearly supported by the gross and histopathological alterations.

Key Words: chronic respiratory disease, mixed respiratory infectious diseases, avian diseases.

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v.6, n.2, 13

Original Full Paper
Throughout Pathological Study on Skin, Subcutaneous and Mucosal Neoplasia of the Dromedary Camel
Fahd A. Al-Sobayil, Yasmin O. El-Amir
Abstract

The aim of this study was to record, classify and describe some external tumors of single-humped camels as well as their diagnosis after surgical excision and to determine the link between occurrence of tumors and breed, sex, age, coat color, and tumor location. Clinical cases of tumors (n =26) were presented for surgical treatment. Camels were subjected to detailed study including breed, age, sex, and coat color of the animal, case history, gross and microscopic appearance of the tumor, surgical treatment, and postoperative care. This study showed that tumors were seen in three local breeds: Maghateer (n=13), Majaheem (n=12), and Sofr (n=1). Four different types of tumors were diagnosed in camels, namely, squamous cell carcinoma (SCC), fibroma, lipoma and fibromyxosarcoma. The most common type of tumor in Maghateer breed which have white colored coat was SCC (69.2%), while in Majaheem breed which have dark brown to black coat was fibroma (66.7%). Incidence of neoplasia was significantly higher in females than males. The age of the animals had no significant effect either on the sitetype of tumor.

Key Words: neoplasia, description, epidemiology, single humped camel.

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v.6, n.2, 14

Original Full Paper
Evaluation of Hypoglycemic Effect of Momordica charantia Extract in Distilled Water in Streptozotocin-Diabetic Rats
Syed Mudasir Ayoub, Suguna Rao, Sonnahallipura Munivenkatappa Byregowda, Mayasandra Laxmikanth Satyanarayana, Narayana Bhat, Narayan Bhat Shridhar, Pragathi Belagola Shridhar
Abstract

Momordica charantiaBitter Melon, a tropical vegetable, is a common food in Indian cuisine and has been used extensively in folk medicine as a remedy for diabetes. The present study was undertaken to evaluate the hypoglycemic effect of Momordica charantia extract in streptozotocin-induced diabetic rat model for a period of 45 days. The alcoholic extract of Momordica charantia was administered orally at the dose rate of 100 and 200 mg/kg body weight in distilled water and compared with standard oral hypoglycemic drug, glibenclamide. In the study a significant (P≤ 0.001) improvement in the physiological and biochemical parameters such as body weight, hemoglobin concentration, serum glucose, cholesterol and triglyceride levels was observed in Momordica charantia treated rats as compared to diabetic control rats. In Momordica charantia treated rats there was gradual and progressive alleviation of streptozotocin effects with M. charantia at higher dose rate (200 mg per kg body weight), more effective in normalizing the pancreatic endocrinal architecture, improving the number of β-cells and in enhancing the insulin secretion. Immunohistochemistry and special staining revealed improvement in the insulin secretion in Momordica charantia and glibenclamide treated groups.

Key Words: hypoglycaemia, bitter melon, streptozotocin, glibenclamide, immunohistochemistry.

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v.6, n.2, 15

Short Communication
Macroscopic and Microscopic Findings in a Set of Congenital Anomalies in Two Calves Produced Through in Vitro Production
Alexandre A. Arenales Torres, Cinthia Lima Lhamas, Delphim da Graça Macoris, Rosemeri de Oliveira Vasconcelos
Abstract

In vitro production and somatic cell nuclear transfer are biotechnologies widely used for breeding cattle, although may result in congenital anomalies. This paper aims to report a set of congenital anomalies in two Nelore calves, a male and a female, produced throughin vitro fertilization. The major anomalies revealed at necropsy were hypospadias, bifid scrotum, atresia ani and rectum ending in blind pouch in the male calf. In the female calf accessory spleen, atresia ani, underdevelopment of extern genitalia and urethral orifice, and rectum ending in blind pouch forming a uterus-rectum fistula were observed.

Key Words: congenital anomalies, hypospadias, accessory spleen, atresia ani, in vitroproduction, bovine.

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v.6, n.2, 16

Case Report
Bone Marrow Involvement in a Dog with Cutaneous Mast Cell Tumor
Sabrina dos Santos Costa Poggiani, Flávia Façanha Viana, Rosana dePaula Branquinho, Fernanda Gomes Velasque Gama
Abstract

Cutaneous mast cell tumors with bone marrow involvement are rarely described in dogs and are associated with a poor prognosis. The aim of this report is to describe a case of bone marrow involvement secondary to cutaneous mast cell tumor in a dog and to discuss clinical and pathological abnormalities associated to this finding. Clinical findings associated with bone marrow infiltration included anemia, thrombocytopenia, staging and recurrent and progressive disease. The dog showed a short survival time. A combination of clinical and laboratory evaluation helps in identifying dogs with this type of tumor with bone marrow involvement, since it is not a common metastatic site reported

Key Words: dog, mastocytoma, metastases, bone marrow, prognosis, skin

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v.6, n.2, 17

Case Report
Anomalous Chordae Tendineae Associated with Mitral Valve Dysplasia in a Cat
Laís Bitencourt Guimarães, Rogéria Serakides, Lorena Gabriela Rocha Ribeiro, Natalia Melo Ocarino
Abstract

A rare case of anomalous chordae tendineae associated with mitral valve dysplasia was observed during necropsy in a 5- year-old male Persian cat with a history of sudden death. Grossly, there was thickening of the mitral valve, which was connected to numerous, short and thickened chordae tendineae that were ectopically inserted into the myocardium. In addition, marked left atrial dilation and pulmonary congestion and edema were present.

Key Words: cat, congenital disease, heart.

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v.6, n.2, 18

Review Article
Zoonotic Diseases from Poultry
Elizabeth Dale, Corrie Brown
Abstract

A wide variety of zoonotic disease risks exists in poultry. Popularity of backyard and smaller production flocks is increasing, as is public concern about global poultry disease events. This paper discusses several of the more common poultry zoonotic diseases, their prevalence and presentation in both poultry and humans.

Key Words: Poultry zoonoses, avian influenza, Newcastle disease, avian tuberculosis,Mycobacterium avium, ornithosis, Chlamydophila psittaci, Erysipelas, Erysipelothrix rhusiopathiae, Salmonella, Campylobacter, Escherichia coli

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v.6, n.2

Corrections
Braz. J. Vet. Pathol., 2011. 4(2), 103-111

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