v.15, n.2, 8
Diagnostic Exercise from The Latin Comparative Pathology Group
Chronic copper poisoning in a sheep
Bianca S. de Cecco, Franciéli A. Molossi, Lauren S. de Mello, Matheus V. Bianchi & Saulo P. Pavarini
Clinical History:
A one-year-old female Texel sheep had anorexia and jaundice. After one day, the clinical condition progressed to lethargy, lateral recumbency, and death within hours. The sheep was part of a flock of 20 housed indoors and received an increasing amount of feed (specific for sheep) for the last two months.
Gross Findings:
The sheep was in excellent body condition. The carcass was discolored by marked icterus (Fig. 1). In the subcutaneous tissue, there was multifocal petechiae and ecchymosis. The kidneys had a deep red-brown discoloration. The urinary bladder was distended and filled with dark red to black urine (Fig. 1). The liver was slightly soft and swollen, with a deep orange hue. The gallbladder was distended and filled with dark grumous bile.
Follow-up questions:
- Cause?
- Pathogenesis?