v.17, n.2, p.108-111, 2024
Case Report
Histopathological and immunohistochemical characterization of a mixed tubule papillary thyroid carcinoma in a Nellore cow
Iolanda Simões Braga, Pedro Pol Ximenes, Fernando Carmona Dinau, Fernanda Barthelson Carvalho de Moura, Isabeli Joaquim Contel, Giovanna Gati de Souza, Isadora Fernanda Pelaquim, Noeme Sousa Rocha
Reports on thyroid carcinomas in bovines are scarce. An 18-year-old Nellore cow was referred to a veterinary hospital due to lateral recumbency lasting one day after falling on irregular terrain. The patient was clinically diagnosed with spinal cord injury. Necropsy and histopathology revealed a thyroid tubule papillary carcinoma. Immunohistochemical analysis revealed discrete positive cells for calcitonin, moderately positive cells for thyroid transcription factor 1 (TTF-1), and strongly positive cells for thyroglobulin in the thyroid gland. Thus, this report describes a case of a mixed tubule papillary carcinoma derived from both medullary and follicular cells in a Nellore cow.
Keywords: bovine, thyroid carcinoma, histopathology, immunohistochemistry.
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