v.17, n.3, p.196-201, 2024
Case Report
Primary paraganglioma-like dermal melanocytic tumor in a dog
Cecilia Ramírez-Hernández, Carlos Ernesto Castro-Valtierra, Jorge Luis García-Valle, Luis Jorge García-Márquez, Rafael Ramírez-Romero
Melanocyte-derived tumors are common in humans and dogs. Their natural presentation in dogs is comparable to that of humans. Therefore, the dog has been proposed as a model in comparative pathology. Melanocyte-derived tumors are highly heterogeneous neoplasms considered the great mimickers because, in rare presentations in humans, their histopathology may include other distinct, unexpected tissue images. The term paraganglioma-like dermal melanocytic tumor refers to a rare neoplasm with a neuroendocrine (paraganglioma) pattern documented in human beings. Twelve cases have been registered to date. A case with these characteristics is herein described in a dog’s skin. To the best of the authors’ knowledge, this is the first case of a dermal melanocytic tumor with the paraganglioma-like pattern described in veterinary pathology.
Keywords: dog, paraganglioma-like dermal melanocytic tumor, chromogranin A, HMB45, Melan A.
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